Product Description: 1,1'-(Azodicarbonyl)-dipiperidine (ADDP) can be used in the condensation reaction of alcohols with acidic compounds. 1,1'-(Azodicarbonyl)-dipiperidine can also be used in the synthesis of GPR120 agonists with antidiabetic activity, as well as the synthesis of triple agonists for PPARα, PPARγ, and PPARδ. 1,1'-(Azodicarbonyl)-dipiperidine can be used in metabolic disease research[1][2][3][4].
Formula: C12H20N4O2
References: [1]Tsunoda T, et al. 1, 1′-(azodicarbonyl) dipiperidine-tributylphosphine, a new reagent system for mitsunobu reaction[J]. Tetrahedron letters, 1993, 34(10): 1639-1642./[2]Hirose D, et al. Systematic Evaluation of 2-Arylazocarboxylates and 2-Arylazocarboxamides as Mitsunobu Reagents. J Org Chem. 2018 Apr 20;83(8):4712-4729./[3]Zhang X, et al. Design, synthesis and SAR of a novel series of heterocyclic phenylpropanoic acids as GPR120 agonists. Bioorg Med Chem Lett. 2017 Aug 1;27(15):3272-3278./[4]Mogensen JP, et al. Design and synthesis of novel PPARalpha/gamma/delta triple activators using a known PPARalpha/gamma dual activator as structural template. Bioorg Med Chem Lett. 2003 Jan 20;13(2):257-60.
CAS Number: 10465-81-3
Molecular Weight: 252.31
Compound Purity: 98.0
Research Area: Metabolic Disease
Target: Free Fatty Acid Receptor;PPAR
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