3-Methyladenine, CAS 5142-23-4

Autophagosome inhibitor

Product Type: Inhibitor

CAS No.: 5142-23-4

MolecularFormula: C6H7N5

Molecular Weight: 149,2

Source: Synthetic

Purity: ≥98%

Solubility: Soluble in DMSO (10 mg/ml) or 100% ethanol (5 mg/ml, warm).

Appearance: White solid.

PubChem CID: 1673

Scientific Background: 3-Methyladenine inhibits phosphatidylinositol 3-kinase (PI3 kinase) and in doing so also is an inhibitor of autophagy by inhibiting autophagosome formation.

References: 1. Blommaart E.F., et al. (1997) Eur J Biochem. 243(1-2): 240-6.2. Lin Y.C., et al. (2012) J Immunol. 189(8): 4154-64.3. Wu Y.T., et al. (2010) J Biol Chem. 285(14): 10850-61.

Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• Artikelnummer: STRSIH-408-20MG
• Hersteller: Stressmarq Biosciences
• Hersteller Artikelnummer: SIH-408-20MG
• Green Labware: Nein
• Verpackungseinheit: 20 mg
• Mengeneinheit: STK