5-HT2A receptor antibody

Application Note: ICC/IF: 10µg/ml. IHC-P: 2µg/ml. FACS: 10ug/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Calculated MW: 53

Specificity/Sensitivity: This antibody is expected to recognize both reported isoforms (NP_000612.1; NP_001159419.1).

Form: Liquid

Buffer (with preservative): Tris saline pH7.3, 0.5% BSA, 0.02% sodium azide.

Concentration: 0.5 mg/ml (Please refer to the vial label for the specific concentration.)

Background: This gene encodes one of the receptors for serotonin, a neurotransmitter with many roles. Mutations in this gene are associated with susceptibility to schizophrenia and obsessive-compulsive disorder, and are also associated with response to the antidepressant citalopram in patients with major depressive disorder (MDD). MDD patients who also have a mutation in intron 2 of this gene show a significantly reduced response to citalopram as this antidepressant downregulates expression of this gene. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]

Uniprot ID: P28223

Antigen Species: Human

Immunogen: Peptide with sequence C-QRSIHREPGSYTGR (aa296-309), from the internal region of the protein sequence according to NP_000612.1; NP_001159419.1.

Purification: Ammonium sulphate precipitation followed by antigen-affinity chromatography

Conjugation: Unconjugated

Full Name: 5-hydroxytryptamine receptor 2A

• Artikelnummer: GTX03473-100
• Hersteller: GeneTex
• Hersteller Artikelnummer: GTX03473-100
• Green Labware: Nein
• Verpackungseinheit: 100 μg
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Polyclonal
• Methode: Immunofluorescence, Immunohistochemistry (paraffin), Flow Cytometry, Immunocytochemistry
• Isotyp: IgG
• Human Gene ID: 3356
• Wirt: Goat