A-803467, CAS 944261-79-4

NaV1.8 blocker

Product Type: Inhibitor

CAS No.: 944261-79-4

MolecularFormula: C19H16ClNO4

Molecular Weight: 357,79

Source: Synthetic

Purity: >98%

Solubility: Soluble to 100 mM in DMSO and to 25 mM in ethanol

Appearance: Beige Solid

PubChem CID: 16038374

Scientific Background: A selective blocker of Nav1.8 channels. A-803467 potently reduced thermal hyperalgesia in inflammatory models of pain and mechanical allodynia in neuropathic models of pain, but was relatively ineffective in a skin-incision model of postoperative pain, a chemotherapy induced pain, and in visceral pain (1).

References: 1. Rush A.M., Cummins T.R. (2007) Mol Interv. 7(4): 192-195.

Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• Artikelnummer: STRSIH-304-50MG
• Hersteller: Stressmarq Biosciences
• Hersteller Artikelnummer: SIH-304-50MG
• Verpackungseinheit: 50 mg
• Mengeneinheit: STK