α-Conotoxin Im-I, CAS 156467-85-5

Product Description: α-Conotoxin Im-I is a selective α7/α9 nAChR antagonist, blocking α7 nicotinic receptors with the highest apparent affinity, while having an 8-fold lower affinity for homomeric α9 nicotinic receptors. α-Conotoxin Im-I is toxic and induces seizures in rodents. α-Conotoxin Im-I is a tool for studying neuronal nAChR[1][2].

Applications: Neuroscience-Neuromodulation

Formula: C52H78N20O15S4

References: [1]Johnson DS, et al. alpha-Conotoxin ImI exhibits subtype-specific nicotinic acetylcholine receptor blockade: preferential inhibition of homomeric alpha 7 and alpha 9 receptors. /[2]Quiram P A, et al. Pairwise interactions between neuronal α7acetylcholine receptors and α-conotoxin PnIB. Journal of Biological Chemistry, 2000, 275(7): 4889-4896.

CAS Number: 156467-85-5

Molecular Weight: 1351.56

Compound Purity: 98.15

Research Area: Neurological Disease

Solubility: DMSO : 100 mg/mL (ultrasonic)

Target: nAChR

• Artikelnummer: MEXHY-P1270-10
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-P1270-10
• Green Labware: Nein
• Verpackungseinheit: 10 mg
• Mengeneinheit: STK