Application Note: WB: 1:500 - 1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 31
Form: Liquid
Buffer (with preservative): PBS, 150mM NaCl, 50% Glycerol, 0.02% sodium azide.
Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration.)
Background: The sphingolipid metabolite sphingosine-1-phosphate promotes cell proliferation and survival, whereas its precursor, sphingosine, has the opposite effect. The ceramidase ACER2 hydrolyzes very long chain ceramides to generate sphingosine (Xu et al., 2006 [PubMed 16940153]).[supplied by OMIM, Jul 2010]
Uniprot ID: Q5QJU3
Antigen Species: Human
Immunogen: A synthesized peptide derived from human ACER2(Accession Q5QJU3), corresponding to amino acid residues L220-K246.
Purification: Purified by antigen-affinity chromatography
Conjugation: Unconjugated
Full Name: alkaline ceramidase 2