Actin Gamma 1 antibody (2A3)

Clone Name: 2A3

Application Note: WB: 1:100 - 1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Calculated MW: 42

Specificity/Sensitivity: This antibody is highly specific for actin gamma and does not react with other actin isoforms (Dugina et al. 2009).

Form: Liquid

Buffer (with preservative): PBS, 0.09% Sodium azide.

Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration.)

Background: Actins are highly conserved proteins that are involved in various types of cell motility and in maintenance of the cytoskeleton. Three main groups of actin isoforms have been identified in vertebrate animals: alpha, beta, and gamma. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. The beta and gamma actins co-exist in most cell types as components of the cytoskeleton and as mediators of internal cell motility. Actin gamma 1, encoded by this gene, is a cytoplasmic actin found in all cell types. Mutations in this gene are associated with DFNA20/26, a subtype of autosomal dominant non-syndromic sensorineural progressive hearing loss and also with Baraitser-Winter syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2017]

Uniprot ID: P63261

Antigen Species: Human

Immunogen: Synthetic peptide corresponding to the N-terminal nonapeptide of gamma-cytoplasmic actin, coupled to KLH.

Purification: Protein A purified

Conjugation: Unconjugated

Full Name: actin gamma 1

• Artikelnummer: GTX03493-100
• Hersteller: GeneTex
• Hersteller Artikelnummer: GTX03493-100
• Green Labware: Nein
• Verpackungseinheit: 100 μg
• Mengeneinheit: STK
• Reaktivität: Human, Mouse (Murine), Rat (Rattus), Monkey (Primate)
• Klonalität: Monoclonal
• Methode: Immunofluorescence, Immunohistochemistry (paraffin), Western Blotting, Immunocytochemistry
• Isotyp: IgG2b
• Human Gene ID: 71
• Wirt: Mouse