Solubility: Soluble in 100% ethanol (25 mg/ml) or DMSO (25 mg/ml)
Appearance: Yellow solid
PubChem CID: 5487525
Scientific Background: AG879 is a selective inhibitor of the tyrosine kinase activity of nerve growth factor (NGF) TrkA. It also inhibits ErbB2 and VEGFR-2.
References: 1. He H., et al. (2004) Cancer Biol. Therapy. 3(1): 96–101.2. Ohmichi M., et al. (1993) Biochem. 32(17): 4650–4658.
Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.