Clone Name: HL3364
Light Chain: Kappa
Form: Liquid
Buffer (with preservative): PBS
Concentration: batch dependent
Background: The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is expressed in endothelial cells, cultured fibroblasts, and osteosarcoma cells. It associates with protein kinases A and C and phosphatase, and serves as a scaffold protein in signal transduction. This protein and RII PKA colocalize at the cell periphery. This protein is a cell growth-related protein. Antibodies to this protein can be produced by patients with myasthenia gravis. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Uniprot ID: Q02952
Antigen Species: Human
Immunogen: Synthetic peptide of human AKAP12.
Purification: Affinity purified by Protein A.
Conjugation: Unconjugated
Full Name: A-kinase anchoring protein 12
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