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ALK antibody (20A85)
ALK antibody (20A85)
Artikelnummer
GTX04501-100
Verpackungseinheit
100 μg
Hersteller
GeneTex
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Clone Name: 20A85
Application Note: ICC/IF: 1:50-1:100. IHC-P: 1:100-1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 176
Form: Liquid
Buffer (with preservative): PBS pH 7.4, 150mM NaCl, 0.4-0.5mg/ml BSA, 50% glycerol, 0.02% Sodium azide.
Concentration: Batch dependent (Please refer to the vial label for the specific concentration.)
Background: This gene encodes a receptor tyrosine kinase, which belongs to the insulin receptor superfamily. This protein comprises an extracellular domain, an hydrophobic stretch corresponding to a single pass transmembrane region, and an intracellular kinase domain. It plays an important role in the development of the brain and exerts its effects on specific neurons in the nervous system. This gene has been found to be rearranged, mutated, or amplified in a series of tumours including anaplastic large cell lymphomas, neuroblastoma, and non-small cell lung cancer. The chromosomal rearrangements are the most common genetic alterations in this gene, which result in creation of multiple fusion genes in tumourigenesis, including ALK (chromosome 2)/EML4 (chromosome 2), ALK/RANBP2 (chromosome 2), ALK/ATIC (chromosome 2), ALK/TFG (chromosome 3), ALK/NPM1 (chromosome 5), ALK/SQSTM1 (chromosome 5), ALK/KIF5B (chromosome 10), ALK/CLTC (chromosome 17), ALK/TPM4 (chromosome 19), and ALK/MSN (chromosome X).[provided by RefSeq, Jan 2011]
Uniprot ID: Q9UM73
Antigen Species: Human
Immunogen: A synthesized peptide, aa410-536, derived from human ALK
Purification: Purified IgG
Conjugation: Unconjugated
Full Name: ALK receptor tyrosine kinase
Application Note: ICC/IF: 1:50-1:100. IHC-P: 1:100-1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 176
Form: Liquid
Buffer (with preservative): PBS pH 7.4, 150mM NaCl, 0.4-0.5mg/ml BSA, 50% glycerol, 0.02% Sodium azide.
Concentration: Batch dependent (Please refer to the vial label for the specific concentration.)
Background: This gene encodes a receptor tyrosine kinase, which belongs to the insulin receptor superfamily. This protein comprises an extracellular domain, an hydrophobic stretch corresponding to a single pass transmembrane region, and an intracellular kinase domain. It plays an important role in the development of the brain and exerts its effects on specific neurons in the nervous system. This gene has been found to be rearranged, mutated, or amplified in a series of tumours including anaplastic large cell lymphomas, neuroblastoma, and non-small cell lung cancer. The chromosomal rearrangements are the most common genetic alterations in this gene, which result in creation of multiple fusion genes in tumourigenesis, including ALK (chromosome 2)/EML4 (chromosome 2), ALK/RANBP2 (chromosome 2), ALK/ATIC (chromosome 2), ALK/TFG (chromosome 3), ALK/NPM1 (chromosome 5), ALK/SQSTM1 (chromosome 5), ALK/KIF5B (chromosome 10), ALK/CLTC (chromosome 17), ALK/TPM4 (chromosome 19), and ALK/MSN (chromosome X).[provided by RefSeq, Jan 2011]
Uniprot ID: Q9UM73
Antigen Species: Human
Immunogen: A synthesized peptide, aa410-536, derived from human ALK
Purification: Purified IgG
Conjugation: Unconjugated
Full Name: ALK receptor tyrosine kinase
| Artikelnummer | GTX04501-100 |
|---|---|
| Hersteller | GeneTex |
| Hersteller Artikelnummer | GTX04501-100 |
| Green Labware | Nein |
| Verpackungseinheit | 100 μg |
| Mengeneinheit | STK |
| Reaktivität | Human, Mouse (Murine), Rat (Rattus) |
| Klonalität | Monoclonal |
| Methode | Immunofluorescence, Immunohistochemistry (paraffin), Immunocytochemistry |
| Isotyp | IgG |
| Human Gene ID | 238 |
| Wirt | Rabbit |
| Produktinformation (PDF) | Download |
| MSDS (PDF) |
|
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