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alpha Synuclein antibody (2A7)
alpha Synuclein antibody (2A7)
Artikelnummer
GTX04298-100
Verpackungseinheit
100 μl
Hersteller
GeneTex
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Clone Name: 2A7
Application Note: WB: 1:1000. ICC/IF: 1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 14
Form: Liquid
Buffer (with preservative): PBS, 50% glycerol, 5mM sodium azide.
Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration.)
Background: Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Alternatively spliced transcripts encoding different isoforms have been identified for this gene. [provided by RefSeq, Feb 2016]
Uniprot ID: P37840
Antigen Species: Human
Immunogen: Full length human recombinant protein expressed in and purified from E. coli
Purification: Purified IgG1
Conjugation: Unconjugated
Full Name: synuclein alpha
Application Note: WB: 1:1000. ICC/IF: 1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 14
Form: Liquid
Buffer (with preservative): PBS, 50% glycerol, 5mM sodium azide.
Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration.)
Background: Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Alternatively spliced transcripts encoding different isoforms have been identified for this gene. [provided by RefSeq, Feb 2016]
Uniprot ID: P37840
Antigen Species: Human
Immunogen: Full length human recombinant protein expressed in and purified from E. coli
Purification: Purified IgG1
Conjugation: Unconjugated
Full Name: synuclein alpha
| Artikelnummer | GTX04298-100 |
|---|---|
| Hersteller | GeneTex |
| Hersteller Artikelnummer | GTX04298-100 |
| Green Labware | Nein |
| Verpackungseinheit | 100 μl |
| Mengeneinheit | STK |
| Reaktivität | Human, Mouse (Murine), Rat (Rattus), Pig (Porcine), Cow (Bovine) |
| Klonalität | Monoclonal |
| Methode | Immunofluorescence, Western Blotting, Immunohistochemistry, Immunocytochemistry |
| Isotyp | IgG1 |
| Human Gene ID | 6622 |
| Wirt | Mouse |
| Produktinformation (PDF) | Download |
| MSDS (PDF) |
|
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Gernot Ensinger, M.Sc.
Laurent Haze
