Ankaflavin, CAS 50980-32-0

Formulation: A solid

Formal Name: (3S,3aR,9aR)-3a,4,8,9a-tetrahydro-(1-oxooctyl)-6-(1E)-1-propen-1-yl-2H-furo[3,2-g][2]benzopyran-2,9(3H)-dione

Purity: ≥98%

Formula Markup: C23H30O5

Formula Weight: 386,5

Shelf life (days): 1460

CAS Number: 50980-32-0

Notes: Ankaflavin is a microbial metabolite that has been found in M. ruber and has diverse biological activities.{69515,69516,69517} It induces cytotoxicity in HepG2 hepatic carcinoma and A549 lung cancer cells (IC50 = ~15 µg/ml for both).{69515} Ankaflavin (15 µg/ml) induces cell cycle arrest at the G0 phase in HepG2 cells. It reduces nitric oxide (NO) production in LPS-stimulated RAW 264.7 macrophages when used at concentrations of 5, 10, and 15 µg/ml.{69516} Ankaflavin (10 µM) increases lipolysis in 3T3-L1 adipocytes matured by isobutylmethylxanthine (IBMX; Item No. 13347), dexamethasone (Item No. 11015), and insulin.{69517} In vivo, ankaflavin (5 mg/kg per day) reduces blood glucose and serum insulin levels in mice fed a high-fat diet.

• Artikelnummer: CAY39546-5
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 39546-5
• Green Labware: Nein
• Verpackungseinheit: 5 mg
• Mengeneinheit: STK