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Products from BPS Bioscience require a minimum order value above 400€Application: CD137 agonist antibody prevents tumor recurrence and metastases in cancer patients. This antibody is useful for activation of CD137 costimulatory pathway in T cells.
Description: Anti-CD137 recombinant human antibody recognizing the CD137 ligand binding region. This antibody not been tested for cross-reactivity with other species.
Format: Aqueous buffer solution
Formulation: 8 mM phosphate, pH 7.4, 110 mM NaCl, 2.2 mM KCl, and 20% glycerol.
Purification: Protein A affinity chromatography from HEK293 supernatants.
Storage Stability: Stable for at least 12 months at -80⁰C. Avoid freeze/thaw cycles. Store diluted antibody with carrier protein (BSA 0.1 - 0.5%) at 4⁰C, stable for 2 weeks.
Uniprot: Q07011
Warnings: Avoid freeze/thaw cycles.
Biosafety Level: Not applicable (BSL-1)
References: 1. Wilcox, R.A., et al., J. Clin. Invest. 2002; 109(5): 651-659.
2. Foell, J. et al., J. Clin. Invest. 2003; 111(10): 1505-1518.