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Application: Targeting CD73 has been shown to prevent tumor recurrence and metastases in cancer patients. Anti-CD73 antibodies have been suggested as a new form of personalized cancer therapy.
Description: Anti-human CD73 recombinant Murine/Human chimeric antagonist antibody. This antibody not been tested for cross reactivity with other species.
Format: Aqueous solution
Formulation: 40 mM Tris-HCl pH 8.0, 110 mM NaCl, 2.2 mM KCl and 20% glycerol.
Purification: Protein A affinity purification from HEK293 supernatants.
Storage Stability: Stable for at least 12 months at -80°C
Supplied As: Aqueous buffer solution.
Warnings: Avoid multiple freeze/thaw cycles.
Biosafety Level: Not applicable (BSL-1)
References: 1. Deaglio, S. et al., J. Exp. Med. 2007;204(6): 1257-1265.2. Thompson, L.F., et al., J. Exp. Med. 2004; 200(11): 1395.