Anti-env

Anti-env, Recombinant, IgG kappa, Rabbit

CloneID: ITS090.03

Antigen Long Description: The original antibody was raised by immunizing a rhesus macaque with the well-characterized neutralization-resistant SIVmac239 strain

Buffer Composition: PBS with 0.02% Proclin 300.

Available Custom Conjugation Options: AP, HRP, Fluorescein, APC, PE, Biotin Type A, Biotin Type B, Streptavidin, FluoroProbes 647H, Atto488, APC/Cy7, PE/Cy7

Uniprot Accession No.: E7CWP5

Specificity Statement: This antibody recognizes a highly glycosylated epitope on the gp120 core.

Application Notes (Clone): The original antibody was used for a virus neutralization assay on SIV Env pseudoviruses. This antibody shows its ability to neutralize this virus (Gorman et al., 2019; PMID:31586542). This antibody was used for an competitive ELISA on SIVmac239 SOSIP.664 (Zhao et al., 2022; PMID:36068229), and on SIVmac239 gp140 FT and SIVmac239 gp120 V1V2V3-deleted gp120 core proteins. The structure of the original antibody was determined using both electron microscopy and x-ray crystallography (Gorman et al., 2019; PMID:31586542) (Zhao et al., 2022; PMID:36068229).

• Artikelnummer: ABAAb04435-23.0
• Hersteller: Absolute Antibody
• Hersteller Artikelnummer: Ab04435-23.0
• Verpackungseinheit: 100 μg
• Mengeneinheit: STK
• Reaktivität: Virus
• Klonalität: Recombinant
• Methode: ELISA, Neutralization, Crystallography
• Isotyp: IgG kappa
• Wirt: Rabbit