Anti-Genome polyprotein (MA28-7)

Anti-Genome polyprotein [MA28-7], Recombinant, IgG1 kappa, Mouse
Artikelnummer
ABAAb04468-1.1
Verpackungseinheit
100 μg
Hersteller
Absolute Antibody

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CloneID: MA28-7

Antigen Long Description: The original antibody was raised by immunizing BALB/c mice with formalin-inactivated EV71 strain 1095.

Buffer Composition: PBS with 0.02% Proclin 300.

Available Custom Conjugation Options: AP, HRP, Fluorescein, APC, PE, Biotin Type A, Biotin Type B, Streptavidin, FluoroProbes 647H, Atto488, APC/Cy7, PE/Cy7

Uniprot Accession No.: Q66479

Specificity Statement: This antibody is specific for binds specifically to the 5-fold vertex encompassing VP1-98E and VP1-244K.

Application Notes (Clone): The original version of this antibody was used for a neutralization assay by preincubating the EV71 (Human enterovirus 71) virus with the antibody and then adding Vero cells. This antibody neutralized only EV71 strains B4, B3 and C2. The structure of the fab version of this antibody was determined using cryo-EM (Lee et al., 2013; PMID:23946455). This antibody was used to immunoprecipitate EV-A71-1095 capsids from solution (Nishimura et al., 2015; PMID:26430888).
Mehr Informationen
Artikelnummer ABAAb04468-1.1
Hersteller Absolute Antibody
Hersteller Artikelnummer Ab04468-1.1
Verpackungseinheit 100 μg
Mengeneinheit STK
Reaktivität Virus
Klonalität Recombinant
Methode Immunoprecipitation, Neutralization
Isotyp IgG1 kappa
Wirt Mouse
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