Anti-GITR Agonist Antibody

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Application: Useful for inhibition of GITR:GITRL interaction.

Assay Conditions: Inhibition of GITR:GITRL interaction with anti-GITR antibody (BPS Bioscience,#79053) through GITR:GITRL TR-FRET Assay Kit (BPS Bioscience #79054). Data in the graphs are expressed as FRET ratios.

Description: Anti-GITR recombinant human antibody recognizing the GITRL binding region of human GITR. This antibody has not been tested for cross-reactivity with any other species.

Format: Aqueous buffer solution

Formulation: 8 mM Na Phosphate pH 7.4, 110 mM NaCl, 2.2 mM KCl and 20% glycerol

Purification: Protein A affinity chromatography from HEK293 supernatants.

Storage Stability: Stable for at least 12 months at -80°C. Avoid freeze/thaw cycles. Store diluted antibody with carrier protein (BSA 0.1 - 0.5%) at 4°C, stable for 2 weeks.

Tags: none

Uniprot: Q9Y5U5

Biosafety Level: Not applicable (BSL-1)

References: 1.Cohen, A., et al., Cancer Research. 2006 May; 66(9): 4904-4912.2.Scumpia, P.O., et al., Blood. 2007 Oct; 110(10):3673-3681.

• Artikelnummer: BPS79053-1
• Hersteller: BPS Bioscience
• Hersteller Artikelnummer: 79053-1
• Verpackungseinheit: 50 µg
• Mengeneinheit: STK
• Klonalität: Monoclonal
• Isotyp: IgG1
• Konjugat: Unconjugated