Bulk anti-Human HLA-DR antibody (L243)

Bulk anti-Human HLA-DR antibody (L243), Host: Mouse, Mouse IgG2a
Artikelnummer
ICH1026-25MG
Verpackungseinheit
25mg
Hersteller
Ichorbio

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Target: HLA-DR.

Clone: L243.

Specificity: Anti-HLA-DR In Vivo Antibody - Low Endotoxin (L243) recognizes/reacts with the HLA-DR antigen, a member of MHC class II molecules. It does not cross-react with HLA-DP and HLA-DQ.

Purification method: This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.

Antigen Distribution: The HLA-DR antigen is present on B-lymphocytes, activated T-lymphocytes and activated natural killer (NK) lymphocytes. This antigen is also expressed on monocytes, macrophages, human progenitor cells and B-cell lymphomas.

Background: HLA-DR is a heterodimeric cell surface glycoprotein comprised of a 36 kD (heavy) chain & a 27 kD (light) chain. It is expressed on B cells, activated T cells, monocytes/macrophages, and dendritic cells. HLA-DR is critical for efficient peptide presentation to CD4+ T cells. Clone L243 binds a conformational epitope on HLA-DRalpha which depends on the correct folding of the Aβ heterodimer.

Immunogen: Unknown.

Concentration: 1.0 mg/ml.

Formulation: No carrier proteins or preservatives added in 0.01 M phosphate buffered saline (PBS) pH 7.2 - 7.4.

Purity: >95% by SDS-PAGE and HPLC.

Endotoxin: ≤ 1.0 EU/mg as determined by the LAL method.

Aggregation: Aggregation level ≤ 5%.

Use: Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Mehr Informationen
Artikelnummer ICH1026-25MG
Hersteller Ichorbio
Hersteller Artikelnummer ICH1026-25MG
Green Labware Nein
Verpackungseinheit 25mg
Mengeneinheit STK
Reaktivität Human
Klonalität Monoclonal
Methode Immunohistochemistry (frozen), Immunoprecipitation, Western Blotting, Flow Cytometry, Blocking, Cytometry by time of flight (CyTOF)
Isotyp Mouse IgG2a
Wirt Mouse
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