Anti-Mouse DNGR-1 In Vivo Antibody – Low Endotoxin (1F6)

Anti-Mouse DNGR-1 In Vivo Antibody – Low Endotoxin (1F6), Host: Rat, Rat IgG1
Artikelnummer
ICH1168-25MG
Verpackungseinheit
25mg
Hersteller
Ichorbio

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Target: DNGR-1.

Clone: 1F6.

Specificity: Clone 1F6 recognizes an epitope on mouse DNGR1.

Purification method: This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.

Antigen Distribution: CD370 (CLEC9A) in mice is expressed on CD8+ DCs and at low levels by plasmacytoid DCs.

Background: CLEC9A, also known as DNGR1 is defined as a type II membrane protein with a single extracellular C-type lectin domain¹. CLEC9A is involved with adaptive immune response during infection. Additionally, CLEC9A, is being investigated for potential to enhance immune responses produced by vaccines.

Immunogen: RBL-2H3 cells expressing mouse DNGR-1 fused to an HA epitope.

Concentration: >2.0 mg/ml.

Formulation: This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (PBS) pH 7.2 – 7.4, 150 mM NaCl with no carrier protein, potassium or preservatives added. BSA and azide free.

Purity: >95% by SDS-PAGE and HPLC.

Endotoxin: ≤ 1.0 EU/mg as determined by the LAL method.

Aggregation: Aggregation level ≤ 5%.

Use: Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Mehr Informationen
Artikelnummer ICH1168-25MG
Hersteller Ichorbio
Hersteller Artikelnummer ICH1168-25MG
Green Labware Nein
Verpackungseinheit 25mg
Mengeneinheit STK
Reaktivität Mouse (Murine)
Klonalität Monoclonal
Methode Immunofluorescence, Western Blotting, Flow Cytometry
Isotyp Rat IgG1
Wirt Rat
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