Target: CD45R
Clone: RA3-6B2
Specificity: Anti-CD45R In Vivo Antibody - Low Endotoxin (RA3-6B2) recognizes the B-cell determinant (Mr 220 kD) of the CD45 molecule.
Purification method: This monoclonal antibody was purified using Protein G
Antigen Distribution: The CD45R antigen is present on mouse B-cells, B-cell precursors, T cell subset, NK cell subsets .
Background: CD45R, also known as B220 is a 220 kDa transmembrane protein tyrosine phosphatase expressed on B cells and some subsets of T and NK cells. This antibody is commonly used as a B cell marker as CD45R does play a critical role in TCR and BCR signaling.
Immunogen: Abelson murine leukemia virus-induced pre-B tumor cells
Concentration: 0.5 mg/ml
Formulation: No carrier proteins or preservatives added in 0.01 M phosphate buffered saline (PBS) pH 7.4, 150 mM NaCl.
Purity: >95% by SDS-PAGE and HPLC
Endotoxin: ≤ 1.0 EU/mg as determined by the LAL method
Aggregation: Aggregation level ≤ 5%
Use: Products are for research use only. Not for use in diagnostic or therapeutic procedures.
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