Anti-Mouse ICAM-1 In Vivo Antibody - Low Endotoxin (BE29G1)

Anti-Mouse ICAM-1 In Vivo Antibody - Low Endotoxin (BE29G1), Host: Rat, Rat IgG2a
Artikelnummer
ICH1101-50MG
Verpackungseinheit
50mg
Hersteller
Ichorbio

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Target: ICAM-1.

Clone: BE29G1.

Specificity: Anti-ICAM-1 In Vivo Antibody - Low Endotoxin (BE29G1) recognizes the (Mr 95 kD) cell surface glycoprotein known as intracellular adhesion molecule ICAM-1. ICAM-1 is the receptor for LFA-1 (CD11a/CD18) and Mac-1 (CD11b/CD18).

Antigen Distribution: The CD54 antigen is present on endothelial cells, lymphocytes, epithelial cells, dendritic cells and keratinocytes. It has been demonstrated that ICAM-1 enhances T-cell activation.

Background: Intercellular adhesion molecule-1 (ICAM-1) is one of an important cell adhesion molecules (CAMs) family transmembrane glycoprotein and is critical for the firm arrest and transmigration of leukocytes out of blood vessels and into tissues. ICAM-1 is constitutively present on endothelial cells, but its expression is increased by proinflammatory cytokines. ICAM-1 is a marker of endothelial dysfunction leading to damaging vascular disorders, in umbilical and placental vascular tissue of gestational pregnancies.

Immunogen: Purified Recombinant Mouse ICAM-1 (>98%).

Concentration: 0.5 mg/ml.

Formulation: 0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added.

Purity: >95% by SDS-PAGE and HPLC.

Endotoxin: ≤ 1.0 EU/mg as determined by the LAL method.

Aggregation: Aggregation level ≤ 5%.

Use: Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Mehr Informationen
Artikelnummer ICH1101-50MG
Hersteller Ichorbio
Hersteller Artikelnummer ICH1101-50MG
Green Labware Nein
Verpackungseinheit 50mg
Mengeneinheit STK
Reaktivität Mouse (Murine)
Methode Immunoprecipitation, Western Blotting, Blocking
Isotyp Rat IgG2a
Wirt Rat
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