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Anti-Mouse IL-1a In Vivo Antibody - Low Endotoxin (ALF-161)
Anti-Mouse IL-1a In Vivo Antibody - Low Endotoxin (ALF-161), Host: Armenian Hamster, Armenian Hamster IgG1
Artikelnummer
ICH1099-50MG
Verpackungseinheit
50mg
Hersteller
Ichorbio
Verfügbarkeit:
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Target: IL-1a.
Clone: ALF-161.
Specificity: Anti-IL-1a In Vivo Antibody - Low Endotoxin (ALF-161) recognizes Mouse IL-1A.
Purification method: This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Background: Mouse IL-1alpha is a non-secreted proinflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells. Both IL-1alpha and IL-1beta binds to the same receptor and has similar if not identical biological properties. These cytokines have a broad range of activities including, stimulation of thymocyte proliferation, by inducing IL-2 release, B-cell maturation and proliferation, mitogenic FGF-like activity and the ability to stimulate the release of prostaglandin and collagenase from synovial cells. However, whereas IL-1beta is a secreted cytokine, IL-1alpha is predominantly a cell-associated cytokine.
Concentration: 1.0 mg/ml.
Formulation: 0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added.
Purity: >95% by SDS-PAGE and HPLC.
Endotoxin: ≤ 1.0 EU/mg as determined by the LAL method.
Aggregation: Aggregation level ≤ 5%.
Use: Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Clone: ALF-161.
Specificity: Anti-IL-1a In Vivo Antibody - Low Endotoxin (ALF-161) recognizes Mouse IL-1A.
Purification method: This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Background: Mouse IL-1alpha is a non-secreted proinflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells. Both IL-1alpha and IL-1beta binds to the same receptor and has similar if not identical biological properties. These cytokines have a broad range of activities including, stimulation of thymocyte proliferation, by inducing IL-2 release, B-cell maturation and proliferation, mitogenic FGF-like activity and the ability to stimulate the release of prostaglandin and collagenase from synovial cells. However, whereas IL-1beta is a secreted cytokine, IL-1alpha is predominantly a cell-associated cytokine.
Concentration: 1.0 mg/ml.
Formulation: 0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added.
Purity: >95% by SDS-PAGE and HPLC.
Endotoxin: ≤ 1.0 EU/mg as determined by the LAL method.
Aggregation: Aggregation level ≤ 5%.
Use: Products are for research use only. Not for use in diagnostic or therapeutic procedures.
| Artikelnummer | ICH1099-50MG |
|---|---|
| Hersteller | Ichorbio |
| Hersteller Artikelnummer | ICH1099-50MG |
| Green Labware | Nein |
| Verpackungseinheit | 50mg |
| Mengeneinheit | STK |
| Reaktivität | Mouse (Murine) |
| Klonalität | Monoclonal |
| Methode | Immunoprecipitation, Western Blotting, ELISA, Flow Cytometry, Neutralization, ELISpot |
| Isotyp | Armenian Hamster IgG1 |
| Wirt | Hamster |
| Produktinformation (PDF) | Download |
| MSDS (PDF) | Download |
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Gernot Ensinger, M.Sc.
Laurent Haze
