Anti-Mouse Ly49C In Vivo Antibody (4LO3311) - Ultra-Low Endotoxin

Anti-Mouse Ly49C In Vivo Antibody (4LO3311) - Ultra-Low Endotoxin, Host: Mouse, Mouse IgG3 kappa

Target: Ly49C.

Clone: 4LO3311.

Specificity: 4LO3311 activity is directed against Ly49C (Killer cell lectin-like receptor 3, KLRA3; NK2.1). 4LO3311 binds an epitope located in a 32-amino acid segment of the stalk region immediately adjacent to the carbohydrate recognition domain.

Purification method: This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.

Antigen Distribution: Ly49C is expressed on NK, uterine NK, NKT, and CD8+ T cells.

Background: 4LO3311 recognizes an epitope located in a 32-amino acid segment of the stalk region immediately adjacent to the carbohydrate recognition domain. 4LO3311 recognizes Ly-49CBALB but not Ly-49AB6, Ly-49ABALB, BBALB, DB6, EB6, FB6, GB6, GBALB, or H. 4LO3311 plus complement inhibits NK cell and antibody-dependent cellular cytotoxicity (ADCC) activity in C3H spleen cells4. 4LO3311 inhibits C57BL/6 and C3H NK cell activity but has no effect on NZB NK cells.

Immunogen: 4LO3311 was generated by immunizing 129/SvJ mice with C57BL/6 NK-enriched spleen cells.

Concentration: ≥ 2.0 mg/ml.

Formulation: Sterile, preservative-free, solution in PBS. BSA and Azide free.

Purity: >98% by SDS-PAGE and HPLC.

Endotoxin: ≤ 0.5 EU/mg as determined by the LAL method.

Aggregation: Aggregation level ≤ 1%.

Use: Products are for research use only. Not for use in diagnostic or therapeutic procedures.

• Artikelnummer: ICH1202UL-25MG
• Hersteller: Ichorbio
• Hersteller Artikelnummer: ICH1202UL-25MG
• Verpackungseinheit: 25mg
• Mengeneinheit: STK
• Reaktivität: Mouse (Murine)
• Klonalität: Monoclonal
• Methode: Immunoprecipitation, Flow Cytometry
• Isotyp: Mouse IgG3 kappa
• Wirt: Mouse