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Anti-Mouse TCR beta In Vivo Antibody – Ultra Low Endotoxin (H57-597)
Anti-Mouse TCR beta In Vivo Antibody – Ultra Low Endotoxin (H57-597), Host: Armenian Hamster, Armenian Hamster IgG
Artikelnummer
ICH1153UL-25MG
Verpackungseinheit
25mg
Hersteller
Ichorbio
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Target: TCR Beta.
Clone: H57-597.
Specificity: Clone H57-597 recognizes an epitope on the constant region of mouse TCRβ. Clone H57-597 does not cross-react with γδ T cells.
Purification method: This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Antigen Distribution: TCRβ is expressed on αβ thymocytes, peripheral T cells, and NKT cells.
Background: TCRβ antibody, clone H57-597, recognizes the beta chain of the T cell receptor (TCRβ), expressed on αβ thymocytes and T lymphocytes, as well as natural killer T (NKT) cells. TCRβ is a transmembrane protein that consists of an amino-terminal variable region, a constant region, and a stalk segment covalently linked to the TCR alpha chain (TCRα) via a disulfide bond. TCRα/β does not contain signaling domains and is instead noncovalently associated with the CD3 complex (TCR-CD3), essential for TCR signaling. TCRα/β recognizes antigens bound to major histocompatibility complex (MHC) molecules, resulting in phosphorylation of CD3 ITAMs and subsequent T cell activation, proliferation, and survival.
Immunogen: Affinity purified TCR from mouse DO-11.10 cells.
Concentration: ≥ 5.0 mg/ml.
Formulation: This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added.
Purity: >98% by SDS-PAGE and HPLC.
Endotoxin: ≤ 0.75 EU/mg as determined by the LAL method.
Aggregation: Aggregation level ≤ 1%.
Use: Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Clone: H57-597.
Specificity: Clone H57-597 recognizes an epitope on the constant region of mouse TCRβ. Clone H57-597 does not cross-react with γδ T cells.
Purification method: This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Antigen Distribution: TCRβ is expressed on αβ thymocytes, peripheral T cells, and NKT cells.
Background: TCRβ antibody, clone H57-597, recognizes the beta chain of the T cell receptor (TCRβ), expressed on αβ thymocytes and T lymphocytes, as well as natural killer T (NKT) cells. TCRβ is a transmembrane protein that consists of an amino-terminal variable region, a constant region, and a stalk segment covalently linked to the TCR alpha chain (TCRα) via a disulfide bond. TCRα/β does not contain signaling domains and is instead noncovalently associated with the CD3 complex (TCR-CD3), essential for TCR signaling. TCRα/β recognizes antigens bound to major histocompatibility complex (MHC) molecules, resulting in phosphorylation of CD3 ITAMs and subsequent T cell activation, proliferation, and survival.
Immunogen: Affinity purified TCR from mouse DO-11.10 cells.
Concentration: ≥ 5.0 mg/ml.
Formulation: This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added.
Purity: >98% by SDS-PAGE and HPLC.
Endotoxin: ≤ 0.75 EU/mg as determined by the LAL method.
Aggregation: Aggregation level ≤ 1%.
Use: Products are for research use only. Not for use in diagnostic or therapeutic procedures.
| Artikelnummer | ICH1153UL-25MG |
|---|---|
| Hersteller | Ichorbio |
| Hersteller Artikelnummer | ICH1153UL-25MG |
| Green Labware | Nein |
| Verpackungseinheit | 25mg |
| Mengeneinheit | STK |
| Reaktivität | Mouse (Murine) |
| Klonalität | Monoclonal |
| Methode | Immunohistochemistry (frozen), Immunohistochemistry (paraffin), Immunoprecipitation, Flow Cytometry |
| Isotyp | Armenian Hamster IgG |
| Wirt | Hamster |
| Produktinformation (PDF) | Download |
| MSDS (PDF) | Download |
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Gernot Ensinger, M.Sc.
Laurent Haze
