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Anti-PCNA Antibody Picoband™ (monoclonal, 2G2)
Anti-PCNA Antibody Picoband™ (monoclonal, 2G2)
Artikelnummer
SANMON23822
Verpackungseinheit
100μg
Hersteller
Sanbio / Monosan
Verfügbarkeit:
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Clone Number: 2G2
Immunogen: E.coli-derived human PCNA recombinant protein (Position: M1-S261).
Concentration: Adding 0.2 ml of distilled water =f 500 μg/ml.
Format: Lyophilized
Storage buffer: Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Additional info: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml. Background: Proliferating cell nuclear antigen (PCNA) is a DNA clamp that acts as a processivity factor for DNA polymerase δ in eukaryotic cells and is essential for replication. It is mapped to 20p12.3. The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome. Subcellular Localization: Tissue Specificity:
Immunogen: E.coli-derived human PCNA recombinant protein (Position: M1-S261).
Concentration: Adding 0.2 ml of distilled water =f 500 μg/ml.
Format: Lyophilized
Storage buffer: Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Additional info: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml. Background: Proliferating cell nuclear antigen (PCNA) is a DNA clamp that acts as a processivity factor for DNA polymerase δ in eukaryotic cells and is essential for replication. It is mapped to 20p12.3. The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome. Subcellular Localization: Tissue Specificity:
| Artikelnummer | SANMON23822 |
|---|---|
| Hersteller | Sanbio / Monosan |
| Hersteller Artikelnummer | MON23822 |
| Green Labware | Nein |
| Verpackungseinheit | 100μg |
| Mengeneinheit | STK |
| Reaktivität | Human, Mouse (Murine), Rat (Rattus) |
| Klonalität | Monoclonal |
| Methode | Immunofluorescence, Western Blotting, Flow Cytometry, Immunohistochemistry, Immunocytochemistry |
| Isotyp | IgG2b |
| Wirt | Mouse |
| Produktinformation (PDF) |
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| MSDS (PDF) |
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Gernot Ensinger, M.Sc.
Laurent Haze
