Apigenin, CAS 520-36-5

Protein kinase inhibitor

Product Type: Inhibitor

CAS No.: 520-36-5

MolecularFormula: C15H10O5

Molecular Weight: 270,2

Source: Synthetic

Purity: >98%

Solubility: Soluble to 50 mM in DMSO

Appearance: White Solid

PubChem CID: 5280443

Scientific Background: Apigenin induces a process called autophagia (1). It is a potent inhibitor of CYP2C9, an enzyme responsible for the metabolism of many pharmaceutical drugs in the body (2). Apigenin has also been shown to reverse the adverse effects of cyclosporine (3).

References: 1. Ruela-de-Sousa R.R., et al. (2010) Cell Death and Disease. 1(e19): 1-11.2. Dayong S.I., et al. (2009) Drug Metabolism and Disposition. 37(3): 629-634.3. Chakravarthi S., Wen C.F., Nagaraja H.S. (2009) J Anal Bio Sci. 32(4): 320-327.

Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• Artikelnummer: STRSIH-249-10MG
• Hersteller: Stressmarq Biosciences
• Hersteller Artikelnummer: SIH-249-10MG
• Verpackungseinheit: 10 mg
• Mengeneinheit: STK