Apolipoprotein B antibody (LDL20 + LDL17)

Clone Name: LDL20 + LDL17

Application Note: *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Calculated MW: 516

Specificity/Sensitivity: This antibody is able to detect native human apoB in the form of LDL.

Form: Liquid

Buffer (with preservative): PBS, 0.02% Sodium azide.

Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration.)

Background: This gene product is the main apolipoprotein of chylomicrons and low density lipoproteins. It occurs in plasma as two main isoforms, apoB-48 and apoB-100: the former is synthesized exclusively in the gut and the latter in the liver. The intestinal and the hepatic forms of apoB are encoded by a single gene from a single, very long mRNA. The two isoforms share a common N-terminal sequence. The shorter apoB-48 protein is produced after RNA editing of the apoB-100 transcript at residue 2180 (CAA->UAA), resulting in the creation of a stop codon, and early translation termination. Mutations in this gene or its regulatory region cause hypobetalipoproteinemia, normotriglyceridemic hypobetalipoproteinemia, and hypercholesterolemia due to ligand-defective apoB, diseases affecting plasma cholesterol and apoB levels. [provided by RefSeq, Jul 2008]

Uniprot ID: P04114

Antigen Species: Human

Immunogen: Human LDL

Purification: Protein G purified

Conjugation: Unconjugated

Full Name: apolipoprotein B

• Artikelnummer: GTX02901-250
• Hersteller: GeneTex
• Hersteller Artikelnummer: GTX02901-250
• Green Labware: Nein
• Verpackungseinheit: 250 μg
• Mengeneinheit: STK
• Reaktivität: Human, Monkey (Primate)
• Klonalität: Monoclonal
• Methode: Western Blotting, ELISA, S-ELISA
• Isotyp: IgG2a
• Human Gene ID: 338
• Wirt: Mouse