Description: BAR502 is a dual GPBAR1 and FXR agonist (IC50s: 0.4 μM and 2 μM).
CAS Number: 1612191-86-2
Formula: C25H44O3
Molecular Weight: 392,62
References: Festa C, et al. Exploitation of cholane scaffold for the discovery of potent and selective farnesoid X receptor (FXR) and G-protein coupled bile acid receptor 1 (GP-BAR1) ligands. J Med Chem. 2014 Oct 23;57(20):8477-95.