BCL6 antibody (LN22)

Clone Name: LN22

Application Note: IHC-P: 1:60. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Calculated MW: 79

Form: Liquid

Buffer (with preservative): Tissue culture supernatant, 0.09% Sodium azide.

Concentration:

Background: The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of STAT-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. This gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq, Aug 2015]

Uniprot ID: P41182

Antigen Species: Human

Immunogen: Prokaryotic recombinant protein corresponding to 1–350 amino acids of the N-terminus of the Bcl-6 human oncoprotein molecule.

Purification: Unpurified

Conjugation: Unconjugated

Full Name: BCL6 transcription repressor

• Artikelnummer: GTX01937-500
• Hersteller: GeneTex
• Hersteller Artikelnummer: GTX01937-500
• Green Labware: Nein
• Verpackungseinheit: 500 μl
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Monoclonal
• Methode: Immunohistochemistry (paraffin)
• Isotyp: IgG2b
• Human Gene ID: 604
• Wirt: Mouse