BI-1467335, CAS 1478364-68-9

Formulation: A solid

Formal Name: 4-[[(2E)-2-(aminomethyl)-3-fluoro-2-propen-1-yl]oxy]-N-(1,1-dimethylethyl)-benzamide, monohydrochloride

Purity: ≥95%

Formula Markup: C15H21FN2O2 • HCl

Formula Weight: 316,8

Shelf life (days): 1460

CAS Number: 1478364-68-9

Notes: BI-1467335 is an inhibitor of vascular adhesion protein-1 (VAP-1; IC50 = 50s = >1,000 and >10,000 nM, respectively). Oral administration of BI-1467335 (10 mg/kg per day) reduces plasma total cholesterol, LDL, and glucose levels, as well as decreases the recruitment of macrophages to atherosclerotic lesions and the area of atherosclerotic plaques, in a cholesterol-fed rabbit model.{51654} It reduces neutrophil lung infiltration induced by K. pneumoniae in mice when administered at a dose of 6 mg/kg.{51655} It also reduces airway hyperreactivity in a mouse model of rhinovirus-exacerbated allergy-induced asthma.

• Artikelnummer: CAY30672-10
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 30672-10
• Verpackungseinheit: 10 mg
• Mengeneinheit: STK