BIX-01294, CAS 935693-62-2

HMT inhibitor

Product Type: Inhibitor

CAS No.: 935693-62-2

MolecularFormula: C28H38N6O2*3HCl

Molecular Weight: 600,02

Source: Synthetic

Purity: >98%

Solubility: May be dissolved in DMSO (100 mM) or Water (100 mM)

Appearance: Cream solid

PubChem CID: 25150857

Scientific Background: G9a-like protein and G9a histone lysine methyltransferase inhibitor (IC values are 0.7 and 1.7 µM respectively) that displays no activity at other histone methyltransferases up to 37 µM. Modulates H3K9me2 levels in mammalian cells and potentiates induction of pluripotent stem cells from somatic cells in vitro.

References: 1. Kubicek S., et al. (2007) Mol Cell. 25(3): 473-481.2. Shi Y., et al. (2008) Cell Stem Cell. 3(5): 568-574.3. Chang Y., et al. (2009) Nat Struct Mol Biol. 16(3): 312-317.

Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• Artikelnummer: STRSIH-347-25MG
• Hersteller: Stressmarq Biosciences
• Hersteller Artikelnummer: SIH-347-25MG
• Verpackungseinheit: 25 mg
• Mengeneinheit: STK