Product Type: Inhibitor
CAS No.: 537034-17-6
MolecularFormula: C20H25N3O2
Molecular Weight: 339,4
Source: Synthetic
Purity: >98% (TLC), NMR conforms
Solubility: Soluble in 25 mg/ml DMSO or 10 mg/ml Ethanol
Appearance: Tan Solid
PubChem CID: 9543540
Scientific Background: A novel non-hydroxamic acid HDAC inhibitor. IC50=5-10 µM (HeLa nuclear extract). Induces growth inhibition, proapoptotic and differentiation effects on human leukemia cell lines.
References: 1. Savickiene J., et al. (2006) Eur. J. Pharmacol. 549: 9.2. Herman D., et al. (2006) Nature Chem. Biol. 10: 551.
Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.