BMSpep-57 (hydrochloride)

Product Description: BMSpep-57 hydrochloride is a potent and competitive macrocyclic peptide inhibitor of PD-1/PD-L1 interaction with an IC50 of 7.68 nM. BMSpep-57 hydrochloride binds to PD-L1 with Kds of 19 nM and 19.88 nM in MST and SPR assays, respectively. BMSpep-57 hydrochloride facilitates T cell function by in creasing IL-2 production in PBMCs[1].

Applications: Cancer-programmed cell death

Formula: C89H127ClN24O19S

References: [1]Aravindhan Ganesan, et al. Comprehensive in vitro characterization of PD-L1 small molecule inhibitors.Sci Rep . 2019 Aug 27;9(1):12392.

Molecular Weight: 1904.63

Compound Purity: 99.69

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: PD-1/PD-L1

• Artikelnummer: MEXHY-P3143A-5
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-P3143A-5
• Green Labware: Nein
• Verpackungseinheit: 5 mg
• Mengeneinheit: STK