Bortezomib , CAS 179324-69-7

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CAS Number: 179324-69-7

Description: Potent (Ki, 0.6 nM), specific and reversible proteasome inhibitor; no significant inhibitory activity against other enzymes or receptors. Bortezomib inhibits cell proliferation of H460 cells (human non-small cell lung cancer cell lines) with an IC50 of 0.1 µM and has been associated with suppresion of prostate cancer cell lines with an IC90 of 10 nM.

Format: White to off-white solid.

Purity: ≥99%

Storage Stability: Store at or below -20°C. Solid form is stable at least 12 months from date of receipt, when stored as directed. Do not store aqueous solutions for more than one day.

Warnings: Protect from light. Hygroscopic. Protect from moisture.

Biosafety Level: Not applicable (BSL-1)

References: 1. Bouchard, PR., et al. 55th Annual Meeting of the American College of Veterinary Pathologists (ACVP) & 39th Annual Meeting of the American Society of Clinical Pathology (ASVCP), ACVP and ASVCP (Eds.) (2004).
2. Ling, Y., et al. Clin. Cancer Res. 9: 1145-1154 (2003).
3. Williams, S., et al. Mol. Cancer Ther. 2: 835-843 (2003).

• Artikelnummer: BPS27028-2
• Hersteller: BPS Bioscience
• Hersteller Artikelnummer: 27028-2
• Verpackungseinheit: 10 mg
• Mengeneinheit: STK