BRL-50481, CAS 433695-36-4

PDE7 inhibitor

Product Type: Inhibitor

CAS No.: 433695-36-4

MolecularFormula: C9H12N2O4S

Molecular Weight: 244,26

Source: Synthetic

Purity: >98% (TLC); NMR (Conforms)

Solubility: May be dissolved in DMSO (40 mg/ml) or Ethanol (5 mg/ml)

Appearance: Cream solid

PubChem CID: 2921148

Scientific Background: BRL-50481 is a selective phosphodiesterase 7 (PDE7) inhibitor. In the presence of BRL-50481 the activity of hrPDE7A1 was inhibited against the phosphodiesterase (PDE3) and (PDE4) (1). Studies have suggested a potential role of BRL-50481 in the treatment of osteoporosis (2).

References: 1. Smith J., et al. (2004) Molecular Biology Pharmacology. 66(6): 1679-89. 2. Pekkinen M., et al. (2008) Bone. 43(1): 84-91.

Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• Artikelnummer: STRSIH-374-10MG
• Hersteller: Stressmarq Biosciences
• Hersteller Artikelnummer: SIH-374-10MG
• Verpackungseinheit: 10 mg
• Mengeneinheit: STK