c-Met (phospho Tyr1234) antibody

Calculated MW: 156

Form: Liquid

Buffer (with preservative): PBS, 150mM NaCl, 50% Glycerol, 0.02% Sodium azide.

Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration.)

Background: This gene encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that are linked via disulfide bonds to form the mature receptor. Further processing of the beta subunit results in the formation of the M10 peptide, which has been shown to reduce lung fibrosis. Binding of its ligand, hepatocyte growth factor, induces dimerization and activation of the receptor, which plays a role in cellular survival, embryogenesis, and cellular migration and invasion. Mutations in this gene are associated with papillary renal cell carcinoma, hepatocellular carcinoma, and various head and neck cancers. Amplification and overexpression of this gene are also associated with multiple human cancers. [provided by RefSeq, May 2016]

Uniprot ID: P08581

Antigen Species: Human

Immunogen: A synthesized peptide derived from human c-Met around the phosphorylation site of Tyr1234.

Purification: Purified by affinity purification via sequential chromatography on phospho-peptide and non-phospho-peptide affinity columns

Conjugation: Unconjugated

Full Name: MET proto-oncogene, receptor tyrosine kinase

• Artikelnummer: GTX02868-100
• Hersteller: GeneTex
• Hersteller Artikelnummer: GTX02868-100
• Green Labware: Nein
• Verpackungseinheit: 100 μl
• Mengeneinheit: STK
• Reaktivität: Human, Mouse (Murine), Rat (Rattus)
• Klonalität: Polyclonal
• Methode: Immunofluorescence, Western Blotting, ELISA, Immunocytochemistry
• Isotyp: IgG
• Human Gene ID: 4233
• Wirt: Rabbit