c-Myc antibody (GT168)

Clone Name: GT168

Application Note: WB: 1:500-1:3000. IHC-P: 1:100-1:1000. FACS: 1:50-1:200. IP: 1:100-1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Calculated MW: 49

Positive Control: 293T

Form: Liquid

Buffer (with preservative): PBS, no preservative.

Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration.)

Background: The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene. [provided by RefSeq]

Uniprot ID: P01106

Antigen Species: Human

Immunogen: The immunogen used to generate this antibody corresponds to human c-Myc

Purification: Affinity purified by Protein G.

Conjugation: Unconjugated

Full Name: MYC proto-oncogene, bHLH transcription factor

• Artikelnummer: GTX628459-100
• Hersteller: GeneTex
• Hersteller Artikelnummer: GTX628459-100
• Green Labware: Nein
• Verpackungseinheit: 100 μl
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Monoclonal
• Methode: Immunohistochemistry (paraffin), Immunoprecipitation, Western Blotting, Flow Cytometry
• Isotyp: IgG1
• Human Gene ID: 4609
• Wirt: Mouse