Caldesmon antibody (CALD1/1424R)

Clone Name: CALD1/1424R

Application Note: IHC-P: 1-2 μg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Calculated MW: 93

Specificity/Sensitivity: This antibody recognizes only the 150kDa variant (h-caldesmon) in Western blots of human aortic media extracts and is unreactive with fibroblast extracts from cultivated human foreskin.

Form: Liquid

Buffer (with preservative): 10mM PBS, 0.05% BSA, 0.05% Sodium azide.

Concentration: 200 μg/ml (Please refer to the vial label for the specific concentration.)

Background: This gene encodes a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca(2+)-calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca(2+)-dependent inhibition of smooth muscle contraction. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]

Uniprot ID: Q05682

Antigen Species: Human

Immunogen: Recombinant human full-length CALD1 protein

Purification: Protein A/G purified

Conjugation: Unconjugated

Full Name: caldesmon 1

• Artikelnummer: GTX02598-100
• Hersteller: GeneTex
• Hersteller Artikelnummer: GTX02598-100
• Green Labware: Nein
• Verpackungseinheit: 100 μg
• Mengeneinheit: STK
• Reaktivität: Human, Rat (Rattus)
• Klonalität: Monoclonal
• Methode: Immunohistochemistry (paraffin)
• Isotyp: IgG
• Human Gene ID: 800
• Wirt: Rabbit