Formulation: A solid
Formal Name: L-arginyl-L-phenylalanylglycyl-L-arginyl-L-phenylalanyl-L-leucyl-L-lysyl-L-isoleucyl-L-arginyl-L-arginyl-L-phenylalanyl-L-arginyl-L-prolyl-L-lysyl-L-valyl-L-threonyl-L-isoleucyl-L-threonyl-L-isoleucyl-L-glutaminylglycyl-L-seryl-L-alanyl-L-arginyl-L-phenylalaninamide, trifluoroacetate salt
Purity: ≥98%
Formula Markup: C147H245N51O30 • XCF3COOH
Formula Weight: 3206,9
Shelf life (days): 1460
Notes: Cathelicidin-2 (CATH-2) (128-153) is a synthetic antimicrobial peptide that corresponds to amino acids 128-153 of chicken CATH-2.{69506} It is active against E. coli, S. aureus, S. enteritidis, and B. globigii in a concentration-dependent manner. CATH-2 (128-153) (40 µM) induces hemolysis of isolated chicken erythrocytes but is not cytotoxic to isolated human peripheral blood mononuclear cells (PBMCs). It induces production of chemokine (C-C-motif) ligand 2 (CCL2) and inhibits LPS-induced production of TNF-α, IL-6, IL-8, and IL-10 in isolated human PBMCs.