Cav1.3 Antibody, Clone S48: APC

Mouse Anti-Rat Cav1.3 Monoclonal IgG2a Kappa

Target: Cav1.3

Conjugate: APC

Product Type: Monoclonal

Clone Number: S48

Immunogen: Fusion protein amino acids 859-875 of rat Cav1.3

Swiss-Prot: P27732

Purification: Protein G Purified

Storage Buffer: PBS pH7.4, 50% glycerol, 0.09% sodium azide *Storage buffer may change when conjugated

Concentration: 1 mg/ml

Specificity: Detects ~250kDa. No cross-reactivity against Cav1.2.

Cellular Localization: Membrane,Cell Membrane

Scientific Background: CaV1.3, also known as the calcium channel, voltage-dependent, L type, alpha 1D subunit (CACNA1D), is a human gene. CaV1.3 subunits are primarily expressed in neurons and neuroendocine cells. Some studies suggest however that CaV1.3 is also found in the atria, and may figure prominently in atrial arrhythmias (1). CaV1.3 also carries the primary sensory receptors of the mammalian cochlea, and are also expressed in the electromotile outer hair cells (2).

References: 1. Zhang Z., et al. (2005) Circulation 112: 1936-1944.2. Johnson S.L. and Marcotti W. (2008) The Journal of Physiology. 586: 1029-1042.

Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• Artikelnummer: STRSMC-301D-APC
• Hersteller: Stressmarq Biosciences
• Hersteller Artikelnummer: SMC-301D-APC
• Green Labware: Nein
• Verpackungseinheit: 100 µg
• Mengeneinheit: STK
• Reaktivität: Human, Mouse (Murine), Rat (Rattus)
• Klonalität: Monoclonal
• Methode: Immunofluorescence, Immunoprecipitation, Western Blotting, Immunohistochemistry, Immunocytochemistry
• Isotyp: IgG2a kappa
• Human Gene ID: 29716
• Wirt: Mouse