Cav3.2 Antibody, Clone N55/10: ATTO 390

Mouse Anti-Human Cav3.2 Monoclonal IgG1

Target: Cav3.2

Conjugate: ATTO 390

Product Type: Monoclonal

Clone Number: N55/10 (Formerly sold as S55-10)

Immunogen: Fusion protein amino acids 1019-1293 (II-III loop) of human Cav3.2

Swiss-Prot: O95180

Purification: Protein G Purified

Storage Buffer: PBS pH7.4, 50% glycerol, 0.09% sodium azide *Storage buffer may change when conjugated

Concentration: 1 mg/ml

Specificity: Detects ~260kDa. No cross-reactivity against Cav1.3.

Cellular Localization: Membrane

Scientific Background: CaV3.2 is a protein which in humans is encoded by the CACNA1H gene. Studies suggest certain mutations in this gene lead to childhood absence epilepsy (1, 2). Studies also suggest that the up-regulations of CaV3.2 may participate in the progression of prostate cancer toward an androgen-independent stage (3).

References: 1. Chen Y., et al. (2003) Ann. Neurol. 54(2): 239–43.2. Khosravani H., et al. (2004) J Biol Chem. 279(11): 9681-9684.3. Gackiere F., et al. (2008) J Biol Chem. 283(28): 19872.

Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• Artikelnummer: STRSMC-303D-A390
• Hersteller: Stressmarq Biosciences
• Hersteller Artikelnummer: SMC-303D-A390
• Green Labware: Nein
• Verpackungseinheit: 100 µg
• Mengeneinheit: STK
• Reaktivität: Human, Mouse (Murine), Rat (Rattus)
• Klonalität: Monoclonal
• Methode: Immunofluorescence, Immunoprecipitation, Western Blotting, Immunohistochemistry, Immunocytochemistry
• Isotyp: IgG1
• Human Gene ID: 8912
• Wirt: Mouse