CBL-B (Y363F), His-tag, Biotin-labeled (Human) Recombinant

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Encompassing Amino Acids: 39 - 426

Application: Useful for the study of enzyme kinetics and regulation, to dephosphorylate target substrates and for screening inhibitors.

Description: Human Casitas B-lineage lymphoma proto-oncogene b (CBL-B), also known as E3 ubiquitin-protein ligase CBL-B, RING finger protein 56, and SH3- binding protein CBL-B with Y363F mutation GenBank Accession No. NM_170662, a.a. 39 - 426 with N-terminal His-tag and N-terminal Avi-tag, expressed in an E. coli expression system. This protein was enzymatically biotinylated in vivo using AviTag™ technology. MW=48 kDa.

Format: Aqueous buffer solution

Formulation: 40 mM Hepesl, pH 7.4, 120mM NaCl, 20% glycerol, 200 mM imidazole

Genbank: NM_170662

Purity: ≥85%

Storage Stability: At least 6 months at -80°C.

Tags: N-terminal His-tag, N-terminal Avi-tag

Uniprot: Q13191

Warnings: Avoid freeze/thaw cycles.

Biosafety Level: Not applicable (BSL-1)

References: 1. Jeon, M.S., et al., Immunity. 2004; 21(2):167-177.2. Chiang, Y.J. et al., Nature. 2000; 403:216-220.

• Artikelnummer: BPS80413-2
• Hersteller: BPS Bioscience
• Hersteller Artikelnummer: 80413-2
• Verpackungseinheit: 50 µg
• Mengeneinheit: STK