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Encompassing Amino Acids: 1-374(end)
Application: Useful for for animal immunization and ELISA.
Background: CCR6 (C-C chemokine receptor type 6), also known as CD196, is expressed mainly in T-cells, B-cells, and lymphocytes. CCR6-mediated signals are critical in inflammatory responses, recruiting IL17-producing T-cells to inflammation sites. Chemokine CCL20 exclusively binds to CCR6, and this ligand-receptor relationship is of interest in studies of inflammatory and autoimmune disorders such as inflammatory bowel disease and psoriasis.
Description: Human CCR6 (C-C chemokine receptor type 6) protein (VLP), full length encompassing amino acids 1-374(end). This construct contains a C-terminal His-tag (10xHis) and was produced using VLP (virus-like particle) technology.
Endotoxin Level: <1 EU/µg (determined by LAL method)
Format: Lyophilized powder
Formulation: Lyophilized from a 0.22 µm filtered solution of Tris/PBS-based buffer, 6% Trehalose, pH 7.4.
Reconstitution: It is not recommended to reconstitute to a concentration less than 100 µg/mL in ddH2O.
Storage Stability: Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is
recommended to freeze aliquots at -20°C or -80°C for extended storage.
Tags: C-terminal His-tag
Uniprot: P51684
Warnings: Avoid freeze/thaw cycles.
Biosafety Level: BSL-1