CCR7 antibody (9L11)

Clone Name: 9L11

Application Note: IHC-P: 1:50 - 1:200. FACS: 1:100 - 1:800. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Calculated MW: 43

Form: Liquid

Buffer (with preservative): PBS, no preservative.

Concentration: 500 μg/ml (Please refer to the vial label for the specific concentration.)

Background: The protein encoded by this gene is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes. It has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor. Signals mediated by this receptor regulate T cell homeostasis in lymph nodes, and may also function in the activation and polarization of T cells, and in chronic inflammation pathogenesis. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Sep 2014]

Uniprot ID: P32248

Antigen Species: Human

Immunogen: Human CCR7 transfected 293 cells

Purification: Protein G purified

Conjugation: Unconjugated

Full Name: C-C motif chemokine receptor 7

• Artikelnummer: GTX52518-50
• Hersteller: GeneTex
• Hersteller Artikelnummer: GTX52518-50
• Green Labware: Nein
• Verpackungseinheit: 50 μg
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Monoclonal
• Methode: Immunohistochemistry (paraffin), Flow Cytometry
• Isotyp: IgG2
• Human Gene ID: 1236
• Wirt: Mouse