CD11c antibody (N418) (PE)

Clone Name: N418

Product Description: The N418 antibody reacts with mouse CD11c, also known as integrin αalpha X. This 150 kDa cell surface glycoprotein is part of a family of integrin αreceptors that mediate adhesion between cells (cell-cell) and components of the extracellular matrix, e.g. fibrinogen (cell-matrix). In addition, integrin αs are active signaling receptors which recruit leukocytes to inflammatory sites and promote cell activation. Complete, functional integrin αreceptors consist of distinct combinations of integrin αchains which are differentially expressed. integrin αalpha X (CD11c) assembles with integrin αbeta-2 (CD18) into a receptor complex known as CR4 which can bind and induce signaling through ICAMs and VCAM-1 on endothelial cells and can also facilitate removal of iC3b bearing foreign cells.

Calculated MW: 129

Form: Liquid

Buffer (with preservative): 10mM NaH₂PO₄, 150mM NaCl, 0.1% Gelatin, 0.09% Sodium azide.

Concentration: 0.2 mg/ml (Please refer to the vial label for the specific concentration.)

Uniprot ID: Q9QXH4

Antigen Species: Mouse

Immunogen: Mouse spleen dendritic cells.

Purification: Purified by affinity chromatography

Conjugation: PE

Full Name: integrin alpha X

• Artikelnummer: GTX74941-100
• Hersteller: GeneTex
• Hersteller Artikelnummer: GTX74941-100
• Green Labware: Nein
• Verpackungseinheit: 100 μg
• Mengeneinheit: PAK
• Reaktivität: Mouse (Murine)
• Klonalität: Monoclonal
• Methode: Flow Cytometry
• Isotyp: IgG2
• Human Gene ID: 16411
• Wirt: Hamster