CD137 antibody (r4-1BB/4603)

Clone Name: r4-1BB/4603

Light Chain: Kappa

Application Note: IHC-P: 2-4 μg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Calculated MW: 28

Form: Liquid

Buffer (with preservative): 10mM PBS, 0.05% BSA, 0.05% Sodium azide.

Concentration: 200 μg/ml (Please refer to the vial label for the specific concentration.)

Background: The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contributes to the clonal expansion, survival, and development of T cells. It can also induce proliferation in peripheral monocytes, enhance T cell apoptosis induced by TCR/CD3 triggered activation, and regulate CD28 co-stimulation to promote Th1 cell responses. The expression of this receptor is induced by lymphocyte activation. TRAF adaptor proteins have been shown to bind to this receptor and transduce the signals leading to activation of NF-kappaB. [provided by RefSeq, Jul 2008]

Uniprot ID: Q07011

Antigen Species: Human

Immunogen: A recombinant fragment (around aa 19-188) of human CD137 protein

Purification: Protein A/G purified

Conjugation: Unconjugated

Full Name: TNF receptor superfamily member 9

• Artikelnummer: GTX02726-100
• Hersteller: GeneTex
• Hersteller Artikelnummer: GTX02726-100
• Green Labware: Nein
• Verpackungseinheit: 100 μg
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Monoclonal
• Methode: Immunohistochemistry (paraffin)
• Isotyp: IgG2a
• Human Gene ID: 3604
• Wirt: Mouse