CD22 / BL-CAM (B-Cell Marker)(BLCAM/1796), 1mg/mL

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Description: This antibody recognizes a protein of 130-140 kDa, identified as CD22 (also known as BL-CAM). CD22 expression is restricted to normal and neoplastic B cells and is absent from other haemopoietic cell types. In B-cell ontogeny, CD22 is first expressed in the cytoplasm of pro-B and pre-B cells, and on the surface as B cells mature to become IgD . It is not expressed by plasma cells, CD22 is found highly expressed in follicular mantle and marginal zone B-cells, and while germinal center B-cells are relatively weak. CD22 is a member of the immunoglobulin superfamily and serves as an adhesion receptor for sialic acid-bearing ligands expressed on erythrocytes and all leukocyte classes. It also associates with tyrosine kinases and play a role in signal transduction and B-cell activation.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Conjugate: Purified, BSA-free

Concentration: 1 mg/mL

Storage buffer: PBS, no BSA, no azide

Product Origin: Animal - Mus musculus (mouse)

Clone: BLCAM/1796

Entrez Gene ID: 933

Immunogen: Recombinant fragment of human CD22 protein (around aa 52-178) (exact sequence is proprietary)

Verified AB Applications: Flow (verified)/IF (verified)/WB (verified)

Z-Antibody Applications: Flow (verified)/IF (verified)/WB (verified)

• Artikelnummer: BTMBNUM1796-50
• Hersteller: Biotium
• Hersteller Artikelnummer: BNUM1796-50
• Verpackungseinheit: 50 uL
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Monoclonal
• Methode: Immunofluorescence, Western Blotting, Flow Cytometry
• Isotyp: IgG2b kappa
• Wirt: Mouse
• Konjugat: Unconjugated