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Encompassing Amino Acids: 27-59
Application: Useful for for animal immunization.
Assay Conditions: Immobilized Human CD24 VLP at 0.5 µg/mL(100 µl/Well) on the plate.
Background: CD24 is a cancer stem cell surface marker highly expressed across many cancer types, including pancreatic, lung, colon, and prostate. CD24 is an important cancer immunotherapy drug target, as it is understood to regulate cell migration, invasion, and proliferation. There are several clinical trials of CD24-targeting drugs, and the future looks promising for the development of anti-CD24 antibodies, antibody-drug conjugates, and CAR-T cell therapies.
Biological Activity: Dose response curve for Anti-CD24 Antibody, hFc Tag with the EC50 of <22.1 ng/mL determined by ELISA.
Description: Human CD24 protein (VLP), encompassing amino acids 27-59. This construct is tag-free and was produced using VLP (virus-like particle) technology.
Endotoxin Level: <1 EU/µg (determined by LAL method)
Format: Aqueous buffer solution
Formulation: Supplied as 0.22 µm filtered solution in PBS (pH 7.4). Notice: If you need it for immunization, Do Not use any adjuvant.
Purity: ≥90% (determined by HPLC)
Storage Stability: Stored at -80°C for 1 year. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
Uniprot: P25063-1
Warnings: Avoid repeated freeze-thaw cycles. If you need it for immunization, Do Not use any adjuvant.
Biosafety Level: BSL-1
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