CD35 antibody (CR1/4382R)

Clone Name: CR1/4382R

Application Note: IHC-P: 1-2 μg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Calculated MW: 224

Form: Liquid

Buffer (with preservative): 10mM PBS, 0.05% BSA, 0.05% Sodium azide.

Concentration: 200 μg/ml (Please refer to the vial label for the specific concentration.)

Background: This gene is a member of the receptors of complement activation (RCA) family and is located in the 'cluster RCA' region of chromosome 1. The gene encodes a monomeric single-pass type I membrane glycoprotein found on erythrocytes, leukocytes, glomerular podocytes, and splenic follicular dendritic cells. The Knops blood group system is a system of antigens located on this protein. The protein mediates cellular binding to particles and immune complexes that have activated complement. Decreases in expression of this protein and/or mutations in its gene have been associated with gallbladder carcinomas, mesangiocapillary glomerulonephritis, systemic lupus erythematosus and sarcoidosis. Mutations in this gene have also been associated with a reduction in Plasmodium falciparum rosetting, conferring protection against severe malaria. Alternate allele-specific splice variants, encoding different isoforms, have been characterized. Additional allele specific isoforms, including a secreted form, have been described but have not been fully characterized. [provided by RefSeq, Jul 2008]

Uniprot ID: P17927

Antigen Species: Human

Immunogen: Synthetic peptide corresponding to human CD35 residues within aa1939-2039

Purification: Protein A/G purified

Conjugation: Unconjugated

Full Name: complement C3b/C4b receptor 1 (Knops blood group)

• Artikelnummer: GTX02623-100
• Hersteller: GeneTex
• Hersteller Artikelnummer: GTX02623-100
• Green Labware: Nein
• Verpackungseinheit: 100 μg
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Monoclonal
• Methode: Immunohistochemistry (paraffin)
• Isotyp: IgG
• Human Gene ID: 1378
• Wirt: Rabbit