CD3e (T-Cell Marker)(UCHT1), 1mg/mL

CD3e (T-Cell Marker)(UCHT1), 1mg/mL
Artikelnummer
BTMBNUM2473-50
Verpackungseinheit
50 uL
Hersteller
Biotium

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Description: Recognizes the epsilon-chain of CD3, which consists of five different polypeptide chains (designated as gamma, delta, epsilon, zeta, and eta) with MW ranging from 16-28 kDa. The CD3 complex is closely associated at the lymphocyte cell surface with the T cell antigen receptor (TCR). Reportedly, CD3 complex is involved in signal transduction to the T cell interior following antigen recognition. The CD3 antigen is first detectable in early thymocytes and probably represents one of the earliest signs of commitment to the T cell lineage. In cortical thymocytes, CD3 is predominantly intra-cytoplasmic. However, in medullary thymocytes, it appears on the T cell surface. CD3 antigen is a highly specific marker for T cells, and is present in majority of T cell neoplasms.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Conjugate: Purified, BSA-free

Concentration: 1 mg/mL

Storage buffer: PBS, no BSA, no azide

Product Origin: Animal - Mus musculus (mouse)

Clone: UCHT1

Entrez Gene ID: 916

Immunogen: Human infant thymocytes and peripheral blood lymphocytes from a Sezary Syndrome donor

Expected AB Applications: ELISA (published for clone)/Functional studies (published for clone)/IP (published for clone)/WB (published for clone)

Verified AB Applications: Flow (surface) (verified)/IF (verified)

Z-Antibody Applications: Functional studies (published)/ELISA (published)/Flow, surface (verified)/IF (verified)/IP (published)/WB (published)
Mehr Informationen
Artikelnummer BTMBNUM2473-50
Hersteller Biotium
Hersteller Artikelnummer BNUM2473-50
Verpackungseinheit 50 uL
Mengeneinheit STK
Reaktivität Human, Primate
Klonalität Monoclonal
Methode Immunofluorescence, Immunoprecipitation, Western Blotting, ELISA, Flow Cytometry, Functional Studies
Isotyp IgG1 kappa
Wirt Mouse
Konjugat Unconjugated
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